BDBM23498 (3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL207729::TMI-1

SMILES: CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO

InChI Key: InChIKey=CVZIHNYAZLXRRS-UHFFFAOYSA-N

Data: 18 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 23498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70	n/a	n/a	n/a	n/a	7.4	22
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Collagenase 3 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
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Interstitial collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Interstitial collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	7.4	22
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					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	22
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A disintegrin and metalloproteinase with thrombospondin motifs 4 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	37
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Matrix metalloproteinase-14 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	22
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Matrix metalloproteinase-9 (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	22
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Matrilysin (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	7.4	22
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					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interstitial collagenase (Human)	BDBM23498 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	7.4	22
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					More data for this Ligand-Target Pair