BDBM23502 beta-sulfonyl hydroxamate analogue, 7::tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate

SMILES: CC#CCNc1ccc(cc1)S(=O)(=O)CC2(CCN(CC2)C(=O)OC(C)(C)C)C(=O)NO

InChI Key: InChIKey=RXFCFGLSOUOCEA-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Human)	BDBM23502 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM23502 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Collagenase 3 (Human)	BDBM23502 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Human)	BDBM23502 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair