BDBM23519 2-[3-(4-phenylphenyl)propanamido]benzoic acid::Biaryl Anthranilide Analogue, 1c::CHEMBL235741

SMILES OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CAYOKBAXZPGNTO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23519   

TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23519(2-[3-(4-phenylphenyl)propanamido]benzoic acid | Bi...)
Affinity DataIC50:  94nM EC50:  590nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23519(2-[3-(4-phenylphenyl)propanamido]benzoic acid | Bi...)
Affinity DataIC50:  290nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23519(2-[3-(4-phenylphenyl)propanamido]benzoic acid | Bi...)
Affinity DataEC50:  590nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed