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BDBM235402 US9359338, Exe. 012

SMILES: FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3cc(NC(=O)C4CC4)ncn3)c2)ccc1Cl

InChI Key: InChIKey=ZUZGEULUDIBXHS-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235402   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 (VEGFR2)


(Homo sapiens (Human))
BDBM235402
PNG
(US9359338, Exe. 012)
Show SMILES FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3cc(NC(=O)C4CC4)ncn3)c2)ccc1Cl
Show InChI InChI=1S/C22H17ClF3N5O3/c23-17-7-6-14(9-16(17)22(24,25)26)30-21(33)29-13-2-1-3-15(8-13)34-19-10-18(27-11-28-19)31-20(32)12-4-5-12/h1-3,6-12H,4-5H2,(H2,29,30,33)(H,27,28,31,32)
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 9.90n/an/an/an/an/a30



CROWN BIOSCIENCE INC. (Taiwan)

US Patent


Assay Description
[Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I...


US Patent US9359338 (2016)


BindingDB Entry DOI: 10.7270/Q2KH0M7N
More data for this
Ligand-Target Pair