BDBM23543 2-oxo-N-phenyl-2H-chromene-3-carboxamide::3-Carboxamide-coumarin deriv., 18::JMC521935 Compound 6

SMILES O=C(Nc1ccccc1)c1cc2ccccc2oc1=O

InChI Key InChIKey=IMFBGZCBLOPVCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 23543   

TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataIC50:  4.20E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataIC50:  760nMAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataIC50:  1.31E+4nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed