BDBM23546 3-Carboxamide-coumarin deriv., 36::6-bromo-2-oxo-N-phenyl-2H-chromene-3-carboxamide

SMILES Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc1ccccc1

InChI Key InChIKey=PNVSYOXGZZSDQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23546   

TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataIC50:  2.40E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed