BDBM23555 3-Carboxamide-coumarin deriv., 31::N-(2-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1ccc2oc(=O)c(cc2c1)C(=O)Nc1ccccc1Cl

InChI Key InChIKey=FPUSGBFAZGKFJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23555   

TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataIC50:  3.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed