BDBM23565 3-Carboxamide-coumarin deriv., 42::6,8-dichloro-N-(3-methylphenyl)-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1cccc(NC(=O)c2cc3cc(Cl)cc(Cl)c3oc2=O)c1

InChI Key InChIKey=SONVRVRNPLMRNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23565   

TargetCoagulation factor XII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataIC50:  2.50E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed