BDBM235766 US9359371, Avanafil

SMILES: COc1ccc(CN=c2[nH]c(ncc2C(O)=NCc2ncccn2)N2CCC[C@H]2CO)cc1Cl

InChI Key: InChIKey=WEAJZXNPAWBCOA-UHFFFAOYSA-N

Data: 24 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 235766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.99	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.56	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.0	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.0	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.0	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.9	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.9	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.9	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.9	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.5	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.29	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase [537-875] (Human)	BDBM235766 (US9359371, Avanafil) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair