BDBM235785 CVD-0019439::US9359399, 2

SMILES CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O

InChI Key InChIKey=FWMNVWWHGCHHJJ-SKKKGAJSSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 235785   

TargetKappa-type opioid receptor(Mus musculus (Mouse))
Cara Therapeutics

US Patent
LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)
Affinity DataEC50:  0.0480nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)
Affinity DataIC50:  9.90E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)
Affinity DataEC50:  0.00300nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM235785(CVD-0019439 | US9359399, 2)
Affinity DataEC50:  0.160nMT: 2°CAssay Description:Mouse R1.G1 cells (ATCC, Manassas, Va.) were grown in suspension in high glucose-DMEM (Dulbecco's Modified Eagle's Medium, Cellgro, Herndon, Va.) con...More data for this Ligand-Target Pair
In DepthDetails US Patent