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BDBM235930 US9365511, 43

SMILES: C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=VRVONIJMTZHLRW-AGDOHHJYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235930   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM235930
PNG
(US9365511, 43)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)C(=O)NCCC(O)=O
Show InChI InChI=1/C23H28N2O3/c1-17-3-2-15-25(17)16-13-18-4-6-19(7-5-18)20-8-10-21(11-9-20)23(28)24-14-12-22(26)27/h4-11,17H,2-3,12-16H2,1H3,(H,24,28)(H,26,27)/t17-/s2
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.5n/an/an/an/an/an/a



Arena Pharmaceuticals Inc

US Patent


Assay Description
Compounds of the present invention were evaluated using the human H3 receptor (H3R) HTRF cAMP assay. In this assay, HEK293 cells expressing the human...


US Patent US9365511 (2016)


BindingDB Entry DOI: 10.7270/Q2FJ2FP8
More data for this
Ligand-Target Pair