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BDBM235934 US9365534, HU-909

SMILES: CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@@H]3CC[C@@]2(CO)C3(C)C)c(OC)c1

InChI Key: InChIKey=ORJLSGKGXZBYAI-PPHZAIPVSA-N

Data: 2 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 235934   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM235934
PNG
(US9365534, HU-909)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@@H]3CC[C@@]2(CO)C3(C)C)c(OC)c1
Show InChI InChI=1S/C27H42O3/c1-8-9-10-11-13-25(2,3)20-16-22(29-6)24(23(17-20)30-7)21-15-19-12-14-27(21,18-28)26(19,4)5/h15-17,19,28H,8-14,18H2,1-7H3/t19-,27-/m0/s1
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PC cid
PC sid
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US Patent
56.8 -10.0n/an/an/an/an/a7.430



YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

US Patent


Assay Description
The Kd of CP 55,940 in the isolated CB1 and CB2 receptor expressing membranes was previously determined to be 2.3 nM and 1.5 nM, respectively (see Pe...


US Patent US9365534 (2016)


BindingDB Entry DOI: 10.7270/Q2639NN9
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM235934
PNG
(US9365534, HU-909)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@@H]3CC[C@@]2(CO)C3(C)C)c(OC)c1
Show InChI InChI=1S/C27H42O3/c1-8-9-10-11-13-25(2,3)20-16-22(29-6)24(23(17-20)30-7)21-15-19-12-14-27(21,18-28)26(19,4)5/h15-17,19,28H,8-14,18H2,1-7H3/t19-,27-/m0/s1
PDB

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1.17E+4 -6.84n/an/an/an/an/a7.430



YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

US Patent


Assay Description
The Kd of CP 55,940 in the isolated CB1 and CB2 receptor expressing membranes was previously determined to be 2.3 nM and 1.5 nM, respectively (see Pe...


US Patent US9365534 (2016)


BindingDB Entry DOI: 10.7270/Q2639NN9
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM235934
PNG
(US9365534, HU-909)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@@H]3CC[C@@]2(CO)C3(C)C)c(OC)c1
Show InChI InChI=1S/C27H42O3/c1-8-9-10-11-13-25(2,3)20-16-22(29-6)24(23(17-20)30-7)21-15-19-12-14-27(21,18-28)26(19,4)5/h15-17,19,28H,8-14,18H2,1-7H3/t19-,27-/m0/s1
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PC cid
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US Patent
n/an/a 425n/an/an/an/a7.537



YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

US Patent


Assay Description
Cells were seeded at a density of 10,000 cells per well in poly-L-lysine treated 96-well culture plates (BD Biosciences). The following day wells wer...


US Patent US9365534 (2016)


BindingDB Entry DOI: 10.7270/Q2639NN9
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM235934
PNG
(US9365534, HU-909)
Show SMILES CCCCCCC(C)(C)c1cc(OC)c(C2=C[C@@H]3CC[C@@]2(CO)C3(C)C)c(OC)c1
Show InChI InChI=1S/C27H42O3/c1-8-9-10-11-13-25(2,3)20-16-22(29-6)24(23(17-20)30-7)21-15-19-12-14-27(21,18-28)26(19,4)5/h15-17,19,28H,8-14,18H2,1-7H3/t19-,27-/m0/s1
PDB

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PC cid
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US Patent
n/an/an/an/a 136n/an/a7.5n/a



YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

US Patent


Assay Description
Human CB2 expressing CHO-K1 membranes (5 μg per incubation mixture) were diluted in 50 mM Tris-HCl (pH 7.5) and 0.5 mM EDTA and added to HU comp...


US Patent US9365534 (2016)


BindingDB Entry DOI: 10.7270/Q2639NN9
More data for this
Ligand-Target Pair