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BDBM236535 1-Chloro-10-(2-N,N-dimethylaminoethyl)-4-methylisoindolo[2,1-a]indole (26)

SMILES: CN(C)CCC1=C2C(Cc3ccccc23)c2c1c(Cl)ccc2C

InChI Key: InChIKey=OKSRAZOLMMTRQN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236535   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM236535
PNG
(1-Chloro-10-(2-N,N-dimethylaminoethyl)-4-methyliso...)
Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2c1c(Cl)ccc2C
Show InChI InChI=1S/C21H22ClN/c1-13-8-9-18(22)21-16(10-11-23(2)3)20-15-7-5-4-6-14(15)12-17(20)19(13)21/h4-9,17H,10-12H2,1-3H3
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
104 -9.90n/an/an/an/an/a7.437



Suven Life Sciences Ltd



Assay Description
In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...


J Enzyme Inhib Med Chem 27: 443-50 (2012)


Article DOI: 10.3109/14756366.2011.595713
BindingDB Entry DOI: 10.7270/Q2HD7TJ5
More data for this
Ligand-Target Pair