BDBM236890 US9388171, II-64

SMILES COc1ccc(cc1)[C@@H]1CN(C)C[C@H]1NC(=O)c1ccc2cnc(Nc3cc(C)nn3C)cc2c1

InChI Key InChIKey=UXYSSMZFOQFSRB-BJKOFHAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236890   

TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM236890(US9388171, II-64)
Affinity DataIC50:  5.47nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM236890(US9388171, II-64)
Affinity DataIC50:  2.68nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent