BDBM23721 4-chloro-1-[(2-fluorophenyl)carbonyl]-3,5-dimethyl-1H-pyrazole::N-Benzoylpyrazole deriv., 29
SMILES Cc1nn(C(=O)c2ccccc2F)c(C)c1Cl
InChI Key InChIKey=LGPJDOCFLPQZPI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 23721
Affinity DataKi: 9.00E+3nM ΔG°: -6.88kcal/molepH: 7.5 T: 25°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
Affinity DataAssay Description:Thrombin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration o...More data for this Ligand-Target Pair
Affinity DataAssay Description:Cathepsin D assays were monitored with a Fluoroskan Ascent FL microtiter plate reader at excitation and emission wavelengths of 340 and 390 nm, respe...More data for this Ligand-Target Pair
Affinity DataAssay Description:Kallikrein activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration...More data for this Ligand-Target Pair
Affinity DataAssay Description:Reactions for aminopeptidase M activity were monitored at 405 nm using a SpectraMax Plus microplate reader. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Chymotrypsin activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentrati...More data for this Ligand-Target Pair
Affinity DataAssay Description:Urokinase activity was monitored at excitation and emission wavelengths of 355 and 460 nm, respectively. For all compounds tested, the concentration ...More data for this Ligand-Target Pair