BDBM237225 1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-phenylthiourea (6b)

SMILES COc1cc(CN(C(=S)Nc2ccccc2)c2ccc(Br)cc2)ccc1O

InChI Key InChIKey=RJYYWODNMWZDED-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237225   

TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237225(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50:  1.27E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237225(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50:  1.78E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetETS domain-containing protein Elk-1(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237225(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50:  1.53E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237225(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50:  970nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM237225(1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...)
Affinity DataIC50:  2.27E+4nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed