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BDBM237710 (3aR,5R,6aS)-5-(4- fluorobenzyl)-2-((R)-2- hydroxy-2-(5- hydroxypyridin-2- yl)ethyl)octahydrocyclo- penta[c]pyrrol-5-ol::US10052306, 256

SMILES: O[C@H](CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3)C[C@H]2C1)c1ccc(O)cn1

InChI Key: InChIKey=BXXJFLUUURSGLN-VAKZPMALSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237710   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))
BDBM237710
PNG
((3aR,5R,6aS)-5-(4- fluorobenzyl)-2-((R)-2- hydroxy...)
Show SMILES O[C@H](CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3)C[C@H]2C1)c1ccc(O)cn1
Show InChI InChI=1S/C21H25FN2O3/c22-17-3-1-14(2-4-17)7-21(27)8-15-11-24(12-16(15)9-21)13-20(26)19-6-5-18(25)10-23-19/h1-6,10,15-16,20,25-27H,7-9,11-13H2/t15-,16+,20-,21-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 31.7n/an/an/an/an/an/a



CADENT THERAPEUTICS, INC.

US Patent


Assay Description
To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...


US Patent US10052306 (2018)


BindingDB Entry DOI: 10.7270/Q20R9RD3
More data for this
Ligand-Target Pair