BDBM23780 (2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sulfanyl]propanoic acid::S-Trityl-L-Cysteine (STLC) Analogue, 9

SMILES N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1)C(O)=O

InChI Key InChIKey=BCBSYXGYLMMICN-DEOSSOPVSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23780   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23780((2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sul...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23780((2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sul...)
Affinity DataKi:  200nM ΔG°:  -9.04kcal/molepH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23780((2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sul...)
Affinity DataIC50:  16.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed