BDBM23780 (2R)-2-amino-3-[(naphthalen-2-yldiphenylmethyl)sulfanyl]propanoic acid::S-Trityl-L-Cysteine (STLC) Analogue, 9
SMILES N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1)C(O)=O
InChI Key InChIKey=BCBSYXGYLMMICN-DEOSSOPVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 23780
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 200nM ΔG°: -9.04kcal/molepH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 16.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair