BDBM238218 US9403774, 1

SMILES COC1CCN(CC1)c1cccc2C(N(CCc12)C(=O)c1ccc(N)cc1)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=JWOPOLBQKJNRMK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238218   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM238218(US9403774, 1)
Affinity DataKi:  542nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent