BDBM238365 3-(3-(Methoxycarbonyl)phenyl)-4-cyano-5-(isopropylthio)thiophene-2-carboxylic acid (1q)
SMILES COC(=O)c1cccc(c1)-c1c(sc(SC(C)C)c1C#N)C(O)=O
InChI Key InChIKey=QRIOULZPYXDQKY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 238365
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Centre De Recherche De Gif
Centre De Recherche De Gif
Affinity DataIC50: 620nMpH: 7.5Assay Description:Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on Wallac Victor fluorimeter from Per...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre De Recherche De Gif
Centre De Recherche De Gif
Affinity DataIC50: 6.90E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif
Centre De Recherche De Gif
Affinity DataIC50: 7.00E+3nMAssay Description:Assays were realized on 96-well plates, as described for yeast FTase but octyl-D-glucopyranoside (0.18%) was used instead of CHAPS and the solution c...More data for this Ligand-Target Pair