BDBM23878 3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin-1-yl]-2-[(4-cyclohexylbenzene)sulfonamido]-3-oxopropyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 22

SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6@H](-[#6]-c1cccc(c1)-[#6](-[#7])=[#7])-[#7]S(=O)(=O)c1ccc(cc1)-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1

InChI Key InChIKey=VBKUOMYCYPUADB-SANMLTNESA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23878   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23878(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  89nM ΔG°:  -9.61kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Curacyte Chemistry

LigandPNGBDBM23878(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  120nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23878(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  780nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Curacyte Chemistry

LigandPNGBDBM23878(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  2.30E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Curacyte Chemistry

LigandPNGBDBM23878(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  1.05E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed