BDBM238791 US9394297, 478

SMILES Cc1nc2cccc(-c3cc4c(CCNC4=O)[nH]3)c2nc1N[C@@H]1C[C@@H](C1)NCC(F)F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238791   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238791(US9394297, 478)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238791(US9394297, 478)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent