BDBM23884 3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin-1-yl]-2-{[2-(naphthalen-1-yl)ethane]sulfonamido}-3-oxopropyl]benzene-1-carboximidamide::3-amidinophenylalanine deriv., 28

SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6@H](-[#6]-c1cccc(c1)-[#6](-[#7])=[#7])-[#7]S(=O)(=O)[#6]-[#6]-c1cccc2ccccc12

InChI Key InChIKey=ZDRJUDWYPVWLPK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23884   

TargetSuppressor of tumorigenicity 14 protein(Human)
Curacyte Chemistry

LigandPNGBDBM23884(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  690nM ΔG°:  -8.40kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Curacyte Chemistry

LigandPNGBDBM23884(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  1.50E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetPlasminogen(Human)
Curacyte Chemistry

LigandPNGBDBM23884(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  4.20E+3nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Curacyte Chemistry

LigandPNGBDBM23884(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  5.60E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Curacyte Chemistry

LigandPNGBDBM23884(3-[(2S)-3-[4-(3-carbamimidamidopropanoyl)piperazin...)
Affinity DataKi:  8.00E+4nMAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2008
Entry Details Article
PubMed