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BDBM239068 US9409900, 65

SMILES: CN(C)C(=O)c1ccc(Oc2ccc(Nc3ccccn3)cc2CN2CCCC2=O)cn1

InChI Key: InChIKey=AYUZMIVZEJRKQS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239068   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase


(Mus musculus (Mouse))
BDBM239068
PNG
(US9409900, 65)
Show SMILES CN(C)C(=O)c1ccc(Oc2ccc(Nc3ccccn3)cc2CN2CCCC2=O)cn1
Show InChI InChI=1S/C24H25N5O3/c1-28(2)24(31)20-10-9-19(15-26-20)32-21-11-8-18(27-22-6-3-4-12-25-22)14-17(21)16-29-13-5-7-23(29)30/h3-4,6,8-12,14-15H,5,7,13,16H2,1-2H3,(H,25,27)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.00E+3n/an/a7.1n/a



FUJIAN HAIXI PHARMACEUTICALS, INC.

US Patent


Assay Description
The final assay volume was 200 uL and the final buffer conditions used in this assay were as follows: 25 mM HEPES, 5 mM glucose, 1 mM ATP, 2 mM MgCl2...


US Patent US9409900 (2016)


BindingDB Entry DOI: 10.7270/Q2SF2V3P
More data for this
Ligand-Target Pair