BDBM23933 1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxybenzene::trans-Stilbene Derivative, 4f

SMILES COc1cc(OC)cc(\C=C\c2ccc(F)cc2)c1

InChI Key InChIKey=BXIQOACOSDGVBH-ONEGZZNKSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23933   

TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23933(1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  3.10nM ΔG°:  -10.8kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institut Claudius Regaud

LigandPNGBDBM23933(1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi: >1.00E+5nMAssay Description:Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23933(1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  3.23E+8nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM23933(1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) using N-methyldihydronicotinamide as co-substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed