BDBM23940 1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene::CHEMBL311636::cis-Stilbene Derivative, 5a

SMILES COc1ccc(\C=C/c2cc(OC)cc(OC)c2)cc1

InChI Key InChIKey=GDHNBPHYVRHYCC-PLNGDYQASA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23940   

TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  75nM ΔG°:  -9.03kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Institut Claudius Regaud

LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  132nMAssay Description:Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  1.33E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of tubulin polymerization reported as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed