BDBM23999 5-methyl-5'-(4-methylphenyl)-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazole]-2-one::thiadiazole derivative, 14

SMILES Cc1ccc(cc1)C1=NNC2(S1)C(=O)Nc1ccc(C)cc21

InChI Key InChIKey=JNGJBWPHVXFTBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23999   

LigandPNGBDBM23999(5-methyl-5'-(4-methylphenyl)-1,2-dihydro-3'H-spiro...)
Affinity DataIC50:  3.00E+3nMpH: 7.5 T: 2°CAssay Description:ADAMTS-5 activity was determined using a fluorescence resonance energy transfer (FRET) assay using a QF peptide containing an aggrecanase cleavage si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed