BDBM240147 US9403813, 52

SMILES: Cc1nc(C(=O)N2CC[C@H]2c2nc(no2)-c2ccccc2OC(F)(F)F)c(o1)-c1cccc(C)c1

InChI Key: InChIKey=CAAAVKPMWFIZQW-KRWDZBQOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM240147 (US9403813, 52) Show SMILES Cc1nc(C(=O)N2CC[C@H]2c2nc(no2)-c2ccccc2OC(F)(F)F)c(o1)-c1cccc(C)c1 Show InChI InChI=1S/C24H19F3N4O4/c1-13-6-5-7-15(12-13)20-19(28-14(2)33-20)23(32)31-11-10-17(31)22-29-21(30-35-22)16-8-3-4-9-18(16)34-24(25,26)27/h3-9,12,17H,10-11H2,1-2H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	357	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9403813 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RS2
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM240147 (US9403813, 52) Show SMILES Cc1nc(C(=O)N2CC[C@H]2c2nc(no2)-c2ccccc2OC(F)(F)F)c(o1)-c1cccc(C)c1 Show InChI InChI=1S/C24H19F3N4O4/c1-13-6-5-7-15(12-13)20-19(28-14(2)33-20)23(32)31-11-10-17(31)22-29-21(30-35-22)16-8-3-4-9-18(16)34-24(25,26)27/h3-9,12,17H,10-11H2,1-2H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	37
Actelion Pharmaceuticals Ltd US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9403813 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RS2
					More data for this Ligand-Target Pair