BindingDB logo
myBDB logout

BDBM240756 US9422307, 39

SMILES: CCN1CCN(CC1)c1ccc(Nc2nc(N)c3scc(-c4cnc5ccccc5c4)c3n2)cn1

InChI Key: InChIKey=XOOCPIRFAVQBFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 240756   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))
BDBM240756
PNG
(US9422307, 39)
Show SMILES CCN1CCN(CC1)c1ccc(Nc2nc(N)c3scc(-c4cnc5ccccc5c4)c3n2)cn1
Show InChI InChI=1S/C26H26N8S/c1-2-33-9-11-34(12-10-33)22-8-7-19(15-29-22)30-26-31-23-20(16-35-24(23)25(27)32-26)18-13-17-5-3-4-6-21(17)28-14-18/h3-8,13-16H,2,9-12H2,1H3,(H3,27,30,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+4n/an/an/an/a7.525



Korea Institute of Science and Technology

US Patent


Assay Description
Full sequence FAK was purchased from Cell Signaling (Catalog No.: 7796). ULight-poly GT (PerkinElmer #TRF0100-D), Eu-anti-phospho-Tyr (PT66) (PerkinE...


US Patent US9422307 (2016)


BindingDB Entry DOI: 10.7270/Q29885XC
More data for this
Ligand-Target Pair