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BDBM240792 H-D-Ser-homoPhe-Arg-OH (3)

SMILES: N[C@H](CO)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O

InChI Key: InChIKey=ISXAPWUOYYNLBV-JCUKGLBFNA-N

Data: 4 KI

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 240792   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasminogen


(Homo sapiens (Human))
BDBM240792
PNG
(H-D-Ser-homoPhe-Arg-OH (3))
Show SMILES N[C@H](CO)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1/C19H30N6O5/c20-13(11-26)16(27)24-14(9-8-12-5-2-1-3-6-12)17(28)25-15(18(29)30)7-4-10-23-19(21)22/h1-3,5-6,13-15,26H,4,7-11,20H2,(H,24,27)(H,25,28)(H,29,30)(H4,21,22,23)/t13-,14-,15-/s2
PDB
MMDB

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
5.90E+3n/an/an/an/an/an/a7.4n/a



Medical University of Bialystok



Assay Description
Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...


J Enzyme Inhib Med Chem 28: 639-43 (2013)


Article DOI: 10.3109/14756366.2011.651463
BindingDB Entry DOI: 10.7270/Q2HQ3XTK
More data for this
Ligand-Target Pair
Thrombin and coagulation factor X


(Homo sapiens (Human))
BDBM240792
PNG
(H-D-Ser-homoPhe-Arg-OH (3))
Show SMILES N[C@H](CO)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1/C19H30N6O5/c20-13(11-26)16(27)24-14(9-8-12-5-2-1-3-6-12)17(28)25-15(18(29)30)7-4-10-23-19(21)22/h1-3,5-6,13-15,26H,4,7-11,20H2,(H,24,27)(H,25,28)(H,29,30)(H4,21,22,23)/t13-,14-,15-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
Article
PubMed
1.61E+4n/an/an/an/an/an/a8.4n/a



Medical University of Bialystok



Assay Description
Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...


J Enzyme Inhib Med Chem 28: 639-43 (2013)


Article DOI: 10.3109/14756366.2011.651463
BindingDB Entry DOI: 10.7270/Q2HQ3XTK
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM240792
PNG
(H-D-Ser-homoPhe-Arg-OH (3))
Show SMILES N[C@H](CO)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1/C19H30N6O5/c20-13(11-26)16(27)24-14(9-8-12-5-2-1-3-6-12)17(28)25-15(18(29)30)7-4-10-23-19(21)22/h1-3,5-6,13-15,26H,4,7-11,20H2,(H,24,27)(H,25,28)(H,29,30)(H4,21,22,23)/t13-,14-,15-/s2
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PubMed
2.39E+4n/an/an/an/an/an/a7.5n/a



Medical University of Bialystok



Assay Description
Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...


J Enzyme Inhib Med Chem 28: 639-43 (2013)


Article DOI: 10.3109/14756366.2011.651463
BindingDB Entry DOI: 10.7270/Q2HQ3XTK
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM240792
PNG
(H-D-Ser-homoPhe-Arg-OH (3))
Show SMILES N[C@H](CO)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1/C19H30N6O5/c20-13(11-26)16(27)24-14(9-8-12-5-2-1-3-6-12)17(28)25-15(18(29)30)7-4-10-23-19(21)22/h1-3,5-6,13-15,26H,4,7-11,20H2,(H,24,27)(H,25,28)(H,29,30)(H4,21,22,23)/t13-,14-,15-/s2
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PC cid
PC sid
UniChem
Article
PubMed
5.66E+5n/an/an/an/an/an/a8.8n/a



Medical University of Bialystok



Assay Description
Buffer and 0.1 mL of enzyme solution was added to 0.2 mL of examined compounddissolved in 0.15 M NaCl (as control 0.15 M NaCl). The buffer and the en...


J Enzyme Inhib Med Chem 28: 639-43 (2013)


Article DOI: 10.3109/14756366.2011.651463
BindingDB Entry DOI: 10.7270/Q2HQ3XTK
More data for this
Ligand-Target Pair