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BDBM2416 1-[2-(diphenylmethoxy)ethyl]-2-methyl-5-nitro-1H-imidazole::Diarylmethoxyethylmethylnitroimidazole (DAMNI) 1

SMILES: Cc1ncc(n1CCOC(c1ccccc1)c1ccccc1)[N+]([O-])=O

InChI Key: InChIKey=SBNQDANULLAFPB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2416   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1)
BDBM2416
PNG
(1-[2-(diphenylmethoxy)ethyl]-2-methyl-5-nitro-1H-i...)
Show SMILES Cc1ncc(n1CCOC(c1ccccc1)c1ccccc1)[N+]([O-])=O
Show InChI InChI=1S/C19H19N3O3/c1-15-20-14-18(22(23)24)21(15)12-13-25-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,14,19H,12-13H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Sapienza University of Rome



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


Bioorg Med Chem Lett 10: 253-6 (2000)


Article DOI: 10.1016/s0960-894x(99)00664-2
BindingDB Entry DOI: 10.7270/Q2Q81B7J
More data for this
Ligand-Target Pair