BDBM242085 US9415055, (-)2-chloro-N-[2-(4,4-difluoro-1-piperidyl)-2-(6-methyl-3-pyridyl)ethyl]-6-fluoro-benzamide

SMILES Cc1ccc(cn1)C(CNC(=O)c1c(F)cccc1Cl)N1CCC(F)(F)CC1

InChI Key InChIKey=PSSGFZSWEAPGGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 242085   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242085(US9415055, (-)2-chloro-N-[2-(4,4-difluoro-1-piperi...)
Affinity DataIC50:  22nMpH: 7.4 T: 2°CAssay Description:Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent