BDBM242110 US9415055, (-)2-chloro-N-[2-(4-chlorophenyl)-2-morpholino-ethyl]-3-methoxy-benzamide::US9593105, 112

SMILES COc1cccc(C(=O)NCC(N2CCOCC2)c2ccc(Cl)cc2)c1Cl

InChI Key InChIKey=FATRLUGOOPYEGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 242110   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242110(US9415055, (-)2-chloro-N-[2-(4-chlorophenyl)-2-mor...)
Affinity DataIC50:  1.5nMpH: 7.4 T: 2°CAssay Description:Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242110(US9415055, (-)2-chloro-N-[2-(4-chlorophenyl)-2-mor...)
Affinity DataIC50:  4.20nMAssay Description:Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242110(US9415055, (-)2-chloro-N-[2-(4-chlorophenyl)-2-mor...)
Affinity DataIC50:  1.5nMAssay Description:Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent