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BDBM24243 2-amino-N-[4-(benzyloxy)phenyl]acetamide::Amino acid analog, 2::CHEMBL479960

SMILES: NCC(=O)Nc1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=YJPUATSIKWOSST-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM24243
PNG
(2-amino-N-[4-(benzyloxy)phenyl]acetamide | Amino a...)
Show SMILES NCC(=O)Nc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C15H16N2O2/c16-10-15(18)17-13-6-8-14(9-7-13)19-11-12-4-2-1-3-5-12/h1-9H,10-11,16H2,(H,17,18)
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PC cid
PC sid
PDB
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PDB
Article
PubMed
n/an/a 280n/an/an/an/a7.522



Berlex Biosciences



Assay Description
Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...


Bioorg Med Chem 16: 4963-83 (2008)


Article DOI: 10.1016/j.bmc.2008.03.042
BindingDB Entry DOI: 10.7270/Q2BP013C
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM24243
PNG
(2-amino-N-[4-(benzyloxy)phenyl]acetamide | Amino a...)
Show SMILES NCC(=O)Nc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C15H16N2O2/c16-10-15(18)17-13-6-8-14(9-7-13)19-11-12-4-2-1-3-5-12/h1-9H,10-11,16H2,(H,17,18)
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PC cid
PC sid
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Article
PubMed
n/an/a 135n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay


Bioorg Med Chem Lett 18: 3891-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM24243
PNG
(2-amino-N-[4-(benzyloxy)phenyl]acetamide | Amino a...)
Show SMILES NCC(=O)Nc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C15H16N2O2/c16-10-15(18)17-13-6-8-14(9-7-13)19-11-12-4-2-1-3-5-12/h1-9H,10-11,16H2,(H,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
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PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay


Bioorg Med Chem Lett 18: 3891-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)