BDBM243277 9-(cyclopropylsulfonyl)-3-(3,5- dimethyl-4-isoxazolyl)-7-((3-fluoro- 1-azetidinyl)carbonyl)-9H- carbazole-1-carboxamide::US10053454, Example 21::US10196387, Example 21
SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2n(c3cc(ccc3c2c1)C(=O)N1CC(F)C1)S(=O)(=O)C1CC1
InChI Key InChIKey=FPPMHSHLUYXZBJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 243277
Affinity DataIC50: <50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair