BDBM243349 4-{5-[3-Methy1-5-(4- trifluoromethyl-pyrimidin- 2-ylamino)-phenyl]- oxazol-2-yl}-4,7-diaza- spiro[2.5]octan-8-one::US10053455, 005

SMILES Cc1cc(Nc2nccc(n2)C(F)(F)F)cc(c1)-c1cnc(o1)N1CCNC(=O)C11CC1

InChI Key InChIKey=YYSWMXHUKQVKGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243349   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Ab Science

US Patent
LigandPNGBDBM243349(4-{5-[3-Methy1-5-(4- trifluoromethyl-pyrimidin- 2-...)
Affinity DataIC50: <500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent