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BDBM243658 US9428456, 1.180

SMILES: CC(N1CCC(CC1)C(=O)NC1CCCCC1)c1cccc(NC(=O)c2cc(Cl)ccn2)c1

InChI Key: InChIKey=DESFFPFSGVTKKX-UHFFFAOYNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243658   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-X-C chemokine receptor type 7 (CXCR7)


(Homo sapiens (Human))
BDBM243658
PNG
(US9428456, 1.180)
Show SMILES CC(N1CCC(CC1)C(=O)NC1CCCCC1)c1cccc(NC(=O)c2cc(Cl)ccn2)c1
Show InChI InChI=1/C26H33ClN4O2/c1-18(31-14-11-19(12-15-31)25(32)29-22-7-3-2-4-8-22)20-6-5-9-23(16-20)30-26(33)24-17-21(27)10-13-28-24/h5-6,9-10,13,16-19,22H,2-4,7-8,11-12,14-15H2,1H3,(H,29,32)(H,30,33)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 51n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...


US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair