BDBM244328 US9550763, Compound I-078

SMILES CCc1oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3cccc(Cl)c3)cc2c1C

InChI Key InChIKey=IJYWBQRQBAXDDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244328   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM244328(US9550763, Compound I-078)
Affinity DataIC50:  20nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent