BDBM24470 7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyridazin-3-yl}methoxy)quinoline::AMG-208::Triazolopyridazine, 4

SMILES: COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1

InChI Key: InChIKey=HEAIZQNMNCHNFD-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 24470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	22
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Epidermal/Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase/Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair