BDBM24477 4-(3-{[(7-methoxyquinolin-4-yl)oxy]methyl}-[1,2,4]triazolo[4,3-a]pyridazin-6-yl)-N-methylbenzamide::Triazolopyridazine, 10g

SMILES CNC(=O)c1ccc(cc1)-c1ccc2nnc(COc3ccnc4cc(OC)ccc34)n2n1

InChI Key InChIKey=QODHFZWQDAIVMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24477   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM24477(4-(3-{[(7-methoxyquinolin-4-yl)oxy]methyl}-[1,2,4]...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM24477(4-(3-{[(7-methoxyquinolin-4-yl)oxy]methyl}-[1,2,4]...)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. Mole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed