BDBM24487 3-(3-fluoro-4-{[2-(1-hydroxyethyl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea::CHEMBL256715::thieno[3,2-b]pyridine-based inhibitor, 6b

SMILES CC(O)c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1

InChI Key InChIKey=BHSQJJXTIHCAAO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24487   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24487(3-(3-fluoro-4-{[2-(1-hydroxyethyl)thieno[3,2-b]pyr...)
Affinity DataIC50:  132nMpH: 7.5 T: 2°CAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24487(3-(3-fluoro-4-{[2-(1-hydroxyethyl)thieno[3,2-b]pyr...)
Affinity DataIC50:  132nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24487(3-(3-fluoro-4-{[2-(1-hydroxyethyl)thieno[3,2-b]pyr...)
Affinity DataIC50:  561nMAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed