BDBM24566 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid::CHEMBL295416::JMC515449 Compound 1::Pirinixic acid::Wyeth 14,643

SMILES: Cc1cccc(c1C)Nc2cc(nc(n2)SCC(=O)O)Cl

InChI Key: InChIKey=SZRPDCCEHVWOJX-UHFFFAOYSA-N

Data: 3 KI  10 IC50  6 Kd  64 EC50  2 K_off  1 Other

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 89 hits for monomerid = 24566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.19E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.37E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mouse)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mouse)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	0.360	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.37E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	542	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM24566 (JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair