BindingDB PrimarySearch

BDBM24567 (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate::CHEMBL175247::Orlistat::THLP::Tetrahydrolipstatin::US9328123, Orlistat::Xenical

SMILES: CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

InChI Key: InChIKey=AHLBNYSZXLDEJQ-UHFFFAOYSA-N

Data: 5 KI 62 IC50 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 68 hits for monomerid = 24567
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysophosphatidylserine lipase ABHD12 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Monoacylglycerol lipase ABHD6 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80.7	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty-acid amide hydrolase 1 [30-579] (Rat)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-alpha (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-beta (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-alpha (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor acetylhydrolase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Neutral cholesterol ester hydrolase 1 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysophosphatidylserine lipase ABHD12 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylserine lipase ABHD16A (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase [2202-2509] (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	7.4	37
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Fatty-acid amide hydrolase 1 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
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Monoacylglycerol lipase ABHD6 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Monoacylglycerol lipase ABHD6 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Monoacylglycerol lipase ABHD6 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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Monoacylglycerol lipase ABHD6 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Lysophosphatidylserine lipase ABHD12 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Lysophosphatidylserine lipase ABHD12 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-beta (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-alpha (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Diacylglycerol lipase-alpha (Mouse)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	806	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt-activated lipase (Bovine)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	423	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proteasome subunit beta type-2 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proteasome subunit beta type-5 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proteasome subunit beta type-1 (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM24567 (Tetrahydrolipstatin \| CHEMBL175247 \| Xenical \| (2S...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	600	n/a	n/a	n/a	n/a	6.8	n/a
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