BDBM246666 US9550763, Compound I-319

SMILES Clc1ccc(Cn2c(=O)c(Nc3ccon3)c[nH]\c2=N/c2ccc(Oc3cccc(n3)C#N)cc2)cc1

InChI Key InChIKey=AJCWYQNSACUCGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246666   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM246666(US9550763, Compound I-319)
Affinity DataIC50:  19nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent