BDBM246669 US9550763, Compound I-322

SMILES COCCn1c(=O)cc(Nc2ccc(Oc3cccc(n3)C#N)c(C)n2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key InChIKey=DZKKDFHSPWXYKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246669   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM246669(US9550763, Compound I-322)
Affinity DataIC50:  5nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent