BDBM247371 US9447092, 1

SMILES: Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1

InChI Key: InChIKey=AKJBLKUZXRMECW-UHFFFAOYSA-N

Data: 8 IC50  8 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 247371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [D835H] (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [K663Q] (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [N841I] (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 [R834Q] (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM247371 (US9447092, 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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