BDBM24751 2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinolin-4-yl}oxy)phenyl]-3-methyl-3,4-dihydropyrimidin-4-one::pyrimidone, 22

SMILES: CN1C(=NC=C(C1=O)c2ccc(c(c2)F)Oc3ccnc4c3cc(c(c4)OCCCN5CCOCC5)OC)Cc6ccccc6

InChI Key: InChIKey=PEGWVOKOYYAQEV-UHFFFAOYSA-N

Data: 2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		8.90	-10.9	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
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Vascular endothelial growth factor receptor 2 (Human)	BDBM24751 (2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		422	-8.60	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair