BDBM24763 1-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)(phenyl)methyl]-3,3-dimethylurea::pyrimidone, 41
SMILES COc1cc2nccc(Oc3ccc(cc3F)-c3cnc(C(NC(=O)N(C)C)c4ccccc4)n(C)c3=O)c2cc1OC
InChI Key InChIKey=TWIHIHMDOCRFES-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 24763
Affinity DataKi: 368nM ΔG°: -8.68kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataIC50: 368nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair