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BDBM248318 US9434711, 171

SMILES: [O-][N+](=O)c1ccccc1CN(c1sc2ccccc2c1Br)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=CGPIQJQDYSQDBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248318   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential M8 protein (TRPM8)


(Canis lupus familiaris (Dog))
BDBM248318
PNG
(US9434711, 171)
Show SMILES [O-][N+](=O)c1ccccc1CN(c1sc2ccccc2c1Br)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H15BrN2O4S2/c22-20-17-11-5-7-13-19(17)29-21(20)23(30(27,28)16-9-2-1-3-10-16)14-15-8-4-6-12-18(15)24(25)26/h1-13H,14H2
KEGG

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 19.3n/an/an/an/an/a37



Janssen Pharmaceutica NV

US Patent


Assay Description
The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...


US Patent US9434711 (2016)


BindingDB Entry DOI: 10.7270/Q2H41QB6
More data for this
Ligand-Target Pair