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BDBM248510 US9434711, 404

SMILES: CCCN(c1sc2ccccc2c1C)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=PVPPDFYEOYBGCT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential M8 protein (TRPM8)


(Canis lupus familiaris (Dog))
BDBM248510
PNG
(US9434711, 404)
Show SMILES CCCN(c1sc2ccccc2c1C)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C19H19NO4S2/c1-3-12-20(18-13(2)16-6-4-5-7-17(16)25-18)26(23,24)15-10-8-14(9-11-15)19(21)22/h4-11H,3,12H2,1-2H3,(H,21,22)
KEGG

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/an/a37



Janssen Pharmaceutica NV

US Patent


Assay Description
The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...


US Patent US9434711 (2016)


BindingDB Entry DOI: 10.7270/Q2H41QB6
More data for this
Ligand-Target Pair